Cheesy Pepperoni Pizza Spiral Roll | Easy Pizza Bread

There’s something about the smell of fresh pizza dough baking in the oven that makes any house feel like home. This Jumbo Pepperoni-Stuffed Pizza Spiral is my playful take on classic pizza night—rolled, cheesy, and baked to golden perfection.

Each slice is stuffed with gooey mozzarella, savory pepperoni, and that signature pizzeria flavor. It’s the kind of dish that makes the whole family crowd around the table.

Why you’ll love this Pepperoni Pizza Spiral Roll

If you’re a pizza lover looking to try something different, this spiral is your new favorite.

• Crispy on the outside, soft and cheesy inside
• Loaded with melted mozzarella and savory pepperoni
• Perfect for sharing or slicing into snack-sized rolls
• Just 9 simple ingredients you probably already have
• Ideal for game nights, parties, or family dinners
• Great with your favorite dipping sauces

I grew up helping my mom make pizza dough in her tiny food truck kitchen back in Texas. The smell of rising dough and sizzling pepperoni always meant family time. These days, I bring that same comfort home, but with a fun twist—rolling it into one giant cheesy spiral that pulls apart beautifully.

Ingredients you’ll need

This homemade dough comes together easily and bakes into the perfect base for that cheesy pepperoni filling.

Main ingredients

• 2 cups all-purpose flour (plus extra for dusting)
• 1 packet active dry yeast (for that rise)
• 1 teaspoon sugar (to activate the yeast)
• 1 teaspoon salt (balances flavor)
• ¾ cup warm water (around 110°F—just warm to the touch)
• 1 tablespoon olive oil (adds softness and flavor)
• 1 cup pepperoni slices (use turkey pepperoni for a leaner option)
• 2 cups shredded mozzarella cheese (whole milk melts best)
• ½ cup pizza sauce (for dipping)

Optional add-ons or substitutes

• Use part-skim mozzarella for a lighter version
• Add Italian seasoning to the dough for extra flavor
• Swap pepperoni for mushrooms, spinach, or grilled chicken
• Brush the baked spiral with garlic butter for shine
• Sprinkle Parmesan before baking for a crisp top layer
• Serve with ranch, marinara, or Buffalo Chicken Pasta Salad for a full meal

Step-by-step instructions

This spiral looks impressive but is surprisingly simple to make.

1. Activate the yeast. In a bowl, mix warm water, sugar, and yeast. Let it sit for 5–10 minutes until foamy. (If it doesn’t foam, the yeast might be old—start fresh.)
   
2. Make the dough. Add flour, salt, and olive oil. Mix until a soft dough forms, then knead for 5–7 minutes until smooth. (I like to use my hands—it builds the best texture.)
   
3. Let it rise. Place dough in a greased bowl, cover with a towel, and let it rise in a warm place for 1 hour or until doubled in size.
   
4. Shape the spiral. Roll the dough into a large rectangle. Layer mozzarella and pepperoni evenly across the surface. (Leave a small border on one edge for sealing.)
   
5. Roll and cut. Roll tightly from one long edge into a log, then coil it into a spiral shape. Place on a greased baking sheet. (It should look like a giant cinnamon roll—but savory!)
   
6. Bake. Brush with olive oil and bake at 400°F for 20–25 minutes, until golden brown and bubbly.
   
7. Serve. Let it cool slightly before slicing. Serve with warm pizza sauce for dipping.

Quick reminders:

• Don’t rush the rise—flavor develops with time
• Use a sharp knife or floss to slice clean spirals if making minis
• Bake on parchment for easy cleanup
• Let it cool 5 minutes before serving to avoid cheese spills

Expert tips for success

The secret to perfect pizza spirals? Heat, layering, and timing.

• Make sure your yeast is fresh for the best rise
• Use warm (not hot) water—too hot kills yeast
• Brush edges with olive oil to prevent drying
• Add a pinch of crushed red pepper for spice
• Use a pizza stone if you want a crispier bottom
• Reheat leftovers in the air fryer for a fresh-baked feel
• Let the dough rest between steps for elasticity

These spirals go perfectly with Hot Honey Flatbread Pizza or even a bowl of Creamy Taco Soup when you want that hearty comfort combo.

Serving suggestions

This pizza spiral is a showstopper for gatherings and weeknight dinners alike.

• Serve warm with marinara or ranch dip
• Slice into smaller rolls for party appetizers
• Add a salad for a balanced meal
• Pair with Slow Cooker Chicken Casserole for a cozy dinner
• Drizzle garlic butter and parsley on top for presentation
• Enjoy leftovers cold—just like next-day pizza!

Let your creativity shine—use this recipe as a base for any favorite pizza flavor you love.

Storing and reheating

This spiral keeps its flavor and texture beautifully with a little care.

How to store it

• Let cool completely before storing
• Wrap tightly in foil or plastic wrap
• Refrigerate for up to 4 days
• Freeze up to 2 months (wrap in foil, then bag it)
• Thaw in fridge overnight before reheating

How to reheat it

• Oven: 350°F for 10 minutes for crisp results
• Air fryer: 350°F for 5–6 minutes for quick reheating
• Microwave: 30–45 seconds for soft texture
• Brush with a little olive oil before reheating to keep moisture
• Avoid overheating—it can make the dough tough

Even after reheating, it’s still cheesy, flavorful, and satisfying—like a fresh pizza night every time.

Nutrition (per serving)

Calories: 310 | Protein: 14g | Carbs: 28g | Fat: 15g | Fiber: 2g | Calcium: 20% DV

Frequently asked questions

Final thoughts

This Jumbo Pepperoni-Stuffed Pizza Spiral is the definition of family comfort food—warm, melty, and packed with pizzeria flavor. It’s the perfect blend of fun presentation and homemade goodness. Once you slice into it and see that cheese stretch, you’ll know it’s a keeper.

• Let your dough rise for flavor and fluff
• Load up on cheese for that pull-apart melt
• Slice thick, dip often, and enjoy every bite

Jake

Cheesy Pepperoni Pizza Spiral Roll

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Make this Cheesy Pepperoni Pizza Spiral for a fun, pull-apart twist on pizza night—crispy edges, gooey cheese, and irresistible flavor in every bite!

Print Recipe Pin Recipe

Prep Time 1 hour hr 15 minutes mins

Cook Time 23 minutes mins

Total Time 1 hour hr 38 minutes mins

Servings: 6 servings

Course: Main Course

Cuisine: Italian-American

Calories: 310

Ingredients Equipment Method Nutrition Notes

Ingredients

  

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• 2 cup all-purpose flour (plus extra for dusting)
• 1 packet active dry yeast
• 1 tsp sugar
• 1 tsp salt
• 0.75 cup warm water (about 110°F)
• 1 tbsp olive oil
• 1 cup pepperoni slices (use turkey pepperoni)
• 2 cup shredded mozzarella cheese
• 0.5 cup pizza sauce (for dipping)

Equipment

• mixing bowl for making the dough
• baking sheet to bake the spiral roll

Method

 

1. In a bowl, combine warm water, sugar, and yeast. Let sit for 5–10 minutes until foamy to activate.
2. Add flour, salt, and olive oil to the yeast mixture. Mix into a soft dough, then knead 5–7 minutes until smooth.
3. Place dough in a greased bowl, cover with a towel, and let rise 1 hour until doubled in size.
4. Roll dough into a large rectangle. Layer mozzarella and pepperoni, leaving a border on one edge for sealing.
5. Roll tightly from one long edge into a log, then coil into a spiral. Place on a greased baking sheet.
6. Brush with olive oil and bake at 400°F for 20–25 minutes, until golden brown and bubbly.
7. Let cool 5 minutes before slicing. Serve with warm pizza sauce for dipping.

Nutrition

Calories: 310kcalCarbohydrates: 28gProtein: 14gFat: 15gFiber: 2g

Notes

1. Let the dough rise fully for a soft, flavorful base.
2. Use turkey pepperoni for a lighter, pork-free option.
3. Brush the baked spiral with garlic butter for extra shine and flavor.

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